Dr. Ilse du Plessis is a psychiatrist, educator, and clinician with a strong academic and interdisciplinary foundation. She completed her MBChB at the University of Pretoria in 1996, after which she worked for two years as a medical officer in the Department of Rheumatology at the then Pretoria Academic Hospital. This early exposure helped shape her enduring interest in the interface between body and mind.

She then spent eight years lecturing in the Departments of Physiology and Pharmacology at the University of Pretoria, building a reputation for clear teaching and a deep grasp of medical science. She later specialized in Psychiatry at the same institution and remained there as a full-time consultant after qualifying.

In 2015, Dr. du Plessis moved into full-time private practice at Denmar Psychiatric Hospital, where she continues to work as a psychiatrist with a broad and thoughtful clinical approach. Alongside her private practice, she remains a special lecturer in the Department of Psychiatry at the University of Pretoria and is actively involved in the training of registrars in neurophysiology. Her work is marked by a particular interest in psychoneuroimmunology, reflecting her commitment to understanding the complex interactions between psychological, neurological, and immune processes. With experience spanning rheumatology, physiology, pharmacology, psychiatry, and registrar training, Dr. du Plessis brings a rare depth and breadth to both patient care and medical education